Ok, I'll try to explain this as best I can:
There's 20 seconds left on the shot clock. The score is tied. The other team drives in for a layup, which they make. Nobody has picked up the ball yet (to take it out for an inbounds pass), and I quickly call a timeout, thinking I would get to advance the ball upcourt. When I exit the timeout, the computer team grabs the ball and lays it in for another 2 points!! What the heck!?! Now they're up by 4--I make a 3-pointer but lose the game by 1.
That was the weirdest bug I've ever encountered. When I launched the replay, sure enough, I saw the other team's player score once, pick the ball up, and score again before I got a chance to inbound the ball!!!
I guess the moral of the story is: don't call a timeout until your player has secured the ball and is ready to inbound the ball, or else you may encounter this bug like I did! =)