Don't be fooled, most of those were (clutch) losses, especially the Suns ones, I only won like 1 out of 3 times against the Lakers.
Iverson said it best, practice (mode)!
Don't try to memorize all of the iso moves, try learning a few that you can always rely on.
Mine is cross, double cross, spin, behind the back, half-spin, step back, quick hesitation (moving), spin hop step.
You can use use the face up buttons if you're not yet comfortable using the left stick and left bumper (default configuration) for isomotion but imo the stick is easier if you want to link together iso moves, as seen in that video of Nash against Fisher and Bynum.
When you are familiar with your 'go to moves' in isomotion you can now concentrate learning your favorite players' effective iso moves. With Wade I find that his spin move and step back are quite effective in creating some space for him either to shoot or to drive. With LeBron, it doesn't matter what, you'll always get to the hole.
