Major:
Fix My Player 'freeze'
Fix shadow detail (PC)
Big men should have a little less vertical leap
Big big man (Shaq, D Howard) shouldn't be taking charges.
Fix the charge and steal issue (this can be done by sliders though)
Fix the Save button (I put my substitution method on Manual but doesn't save for me

When players fall down when taking a jumper and getting injured happens too much, so tone that down.
Minor:
Calf Sleeve /w no socks
Less glossy ball
Accessories color (for home, white, away, black, etc)
That's all I can think of and some of this I got it from 2K Forums...