can i ran nba2k12 with my specs

System Model: Inspiron 1546
BIOS: Phoenix ROM BIOS PLUS Version 1.10 A03
Processor: AMD Turion(tm) X2 Dual-Core Mobile RM-75 (2 CPUs), ~2.2GHz
Memory: 4096MB RAM
Available OS Memory: 4094MB RAM
Page File: 1747MB used, 6439MB available
Card name: ATI Mobility Radeon. HD 530v
Manufacturer: ATI Technologies Inc.
Chip type: ATI display adapter (0x9552)
DAC type: Internal DAC(400MHz)
Device Key: Enum\PCI\VEN_1002&DEV_9552&SUBSYS_02FA1028&REV_00
Display Memory: 2296 MB
Dedicated Memory: 505 MB
Shared Memory: 1791 MB
Current Mode: 1366 x 768 (16 bit) (60Hz)

I should think so. Judging by some of the videos of other games using that graphics card on YouTube, it should do the job.

but when i play nba 2k12 the game is laggy and low fps around 15-20

Even when you lower the detail settings?

yes

Are you having similar issues with any other games?

nope

Try the usual troubleshooting methods I guess; update drivers, disable anti-virus while playing, etc.