In my third franchise season (yes, i'm challenged

) i use such settings: Superstar, 4 min qtrs, CPU assit ON, Shot control CPU.
In-game settings (can those be saved to be used for the WHOLE franchise not just for one game? i think no):
Full court press - i manage to get 4-5 steals in their zone (provided their PG is not a superstar). Drawback - increased vulnerability to fastbreaks, since your players on defence will stick like flies to the $hit they own - C to C, PF to PF, etc.
Box out OFF (just a prejudice tho, tried everything, and they still box out)
Crash boards OFF
Autosubs ON (switch OFF in the 4th qtr.).
Rule No. 1: Never take a three-pointer if you're not wide open, because that will usually result in -2 pts. (fastbreak). I have steve nash, brent barry, morris peterson, mike miller (see below to learn how i obtained them) but take only 4-5 3pt attempts/game;
Rule No. 2: C and PF are very prone to TOs and blocks so i best choose a PG, SG or SF, whoever has the highest rating, do a spin and shoot - high chances of scoring, low chances of getting blocked.
I was very lucky after the second season to be the fifth team on the calendar - this way i got access to the pool full of high-rating players with their dumb-ass agents - "want some 80-85 overal-rating player for a minimum? want six of those?" Now it's a lot easier to win.