I'm not sure if anyone is even still reading the general tab, but my myplayer game keeps crashing after the first game played. I tried everything I can think of to make it work. I ran it in windows xp, 7, 8 and 10. The only things I have updated are the courts and URB roster. I haven't done anything else. No cheat engine or trainers. I really want to play this game again. I had no problems when I first got this game way back when it first came out.
Try playing with the default rosters and see if the game still crashes. If it doesn't, you might want to check out the URB release thread for more info about its compatibility with MyCAREER mode.